Dear Canisius,
OptiSystem has Matlab component that you could use to call Matlab which has the Simulink module. However, you need to properly use the input and output signals’ structures. Please refer to the datasheet of the Matlab component for more information on the signal structures. Also, refer to the examples in OptiSystem Example Library for more information.
C:\Users\USER NAME\Documents\OptiSystem 16.1 Samples\Software interworking\MATLAB co-simulation
You can download 30days free trail of OptiSystem 16.1
Regards,
Ahmad