This is an interesting application!
Based on our understanding of OFDM and SC-FDMA there is an additional IDFT block that is required for SC-FDMA systems (both transmit and receive sides). It may be possible to add these functions by using our Matlab component before and after our OFDM modulators and demodulators (as per following enclosed paper). I am not sure this will work, but it’s worth a try.
We are very busy these days working on our OptiSystem 13 release development, but we will try to build an example for this type of application after we release OptiSystem 13 in early July.